THE REAL STORY OF OUR GENETIC COMPLEXITY
Two parallel genomes: MICROBIOME vs GENOME
THE REAL STORY OF OUR GENETIC COMPLEXITY
Two parallel genomes:
MICROBIOME vs GENOME
Microbiome
Collection of all commensal microbial genes in body
TOTAL MICROBIAL CELLS: 40000000
TOTAL GENES: 3000000
Inherited from mother environment,other sources
High variability within and between individuals
Dysbiosis causes desease conditions
Microbiome diversity:monitored easily
High degree of pasticity or adaptability
Can be modulated by targeted interventions
Collection of all human genes in body
Total human celles: 40000000
Total genes:23000
- Inherited from both parents
- Stable limited degree of plasticity
- Genome mutations causes desease conditions
- Diversity:limited
- Gene modulations:risky
Genome
Health & Well-being/Disease prevention/Longevity
Collection of all human genes in body
Total human celles: 40000000
Total genes:23000
- Inherited from both parents
- Stable limited degree of plasticity
- Genome mutations causes desease conditions
- Diversity:limited
- Gene modulations:risky
Genome
Health & Well-being/Disease prevention/Longevity
Human Microbiome:
The human microbiota is the aggregate of microorganisms that resides on the surface and in deep layers of skin, in the saliva and oral mucosa, in the conjunctiva, and in the gastrointestinal tracts and the human microbiome refer to their genomes. The microbiome is reckoned to have around 3 million functional genes compared to human beings 23,000 and the far larger genome of the microbiome has correspondingly greater capabilities in modulating human health and well being. Microbiome’s health and diversity is a growing theme in medical research for treating autoimmune, infectious, and metabolic diseases.
Human Microbiome:
The human microbiota is the aggregate of microorganisms that resides on the surface and in deep layers of skin, in the saliva and oral mucosa, in the conjunctiva, and in the gastrointestinal tracts and the human microbiome refer to their genomes. The microbiome is reckoned to have around 3 million functional genes compared to human beings 23,000 and the far larger genome of the microbiome has correspondingly greater capabilities in modulating human health and well being. Microbiome’s health and diversity is a growing theme in medical research for treating autoimmune, infectious, and metabolic diseases.
Microbiome & Health
Everyone’s got a personal collection of microbiota. You could think of yours as your unique internal pet—at up to 3 percent of your body mass requiring nurturing and feeding. In turn, your microbiota provide essential services: extracting energy from food, absorbing and generating vitamins and amino acids and forming barriers against infective invaders. New studies are showing your microbiota might also fight diabetes, obesity and cancer; stimulate your immune system; break down toxins; and boost your overall health.
The gut microbiota has a crucial role in metabolic health, but researchers are only just determining the mechanisms underpinning this effect. Studies have found that specific class of bacteria that degrades mucin in the gut lining and can have beneficial effects on metabolic disorders, has a key role in systemic glucose metabolism. These classes of bacteria modulates glucose metabolism by altering gene expression of certain key biomolecules in ileum.
Everyone’s microbiome appears to be unique and is readily modified by diet, its multiple microorganisms seem to have overlapping roles and applied microbiome interventions could revolutionize the way we think about gut bacteria in relation to weight loss, immunity, disease and the creation of essential nutrients.Changes in microbiome composition and diversity are associated with the development of metabolic diseases and microbiome is considered as the next big platform for diagnostic and drug discovery for treating autoimmune, metabolic and infectious diseases. There are a number of benefits in microbiome-based approach in controlling or treating metabolic diseases unlike human genome sequence-based interventions. Further, emerging scientific information shows the importance of microbiome in determining your healthy life-span.
We at Biom Pharmaceutical realize the enormous importance of human commensal microbiota. Our research and product development efforts are targeted towards harnessing the potential of microbiome for future personalized medicine and preventative care.
Microbiome & Health
Everyone’s got a personal collection of microbiota. You could think of yours as your unique internal pet—at up to 3 percent of your body mass requiring nurturing and feeding. In turn, your microbiota provide essential services: extracting energy from food, absorbing and generating vitamins and amino acids and forming barriers against infective invaders. New studies are showing your microbiota might also fight diabetes, obesity and cancer; stimulate your immune system; break down toxins; and boost your overall health.
The gut microbiota has a crucial role in metabolic health, but researchers are only just determining the mechanisms underpinning this effect. Studies have found that specific class of bacteria that degrades mucin in the gut lining and can have beneficial effects on metabolic disorders, has a key role in systemic glucose metabolism. These classes of bacteria modulates glucose metabolism by altering gene expression of certain key biomolecules in ileum.
Everyone’s microbiome appears to be unique and is readily modified by diet, its multiple microorganisms seem to have overlapping roles and applied microbiome interventions could revolutionize the way we think about gut bacteria in relation to weight loss, immunity, disease and the creation of essential nutrients.Changes in microbiome composition and diversity are associated with the development of metabolic diseases and microbiome is considered as the next big platform for diagnostic and drug discovery for treating autoimmune, metabolic and infectious diseases. There are a number of benefits in microbiome-based approach in controlling or treating metabolic diseases unlike human genome sequence-based interventions. Further, emerging scientific information shows the importance of microbiome in determining your healthy life-span.
We at Biom Pharmaceutical realize the enormous importance of human commensal microbiota. Our research and product development efforts are targeted towards harnessing the potential of microbiome for future personalized medicine and preventative care.
